Mechanistic Understanding

The exact sequence of bond making and bond breaking processes in a chemical or biochemical transformation is defined as the reaction mechanism. Understanding the precise order of these events adds to our fundamental scientific knowledge and enables the full potential of a process to be realised to prepare complex and high-value compounds more efficiently and more reliably.

The LabFact partners are developing mechanistic understanding in many different areas but in particular using techniques for reagentless synthesis.

Key Abstracts

(N-Heterocyclic Carbene)2‑Pd(0)-Catalyzed Silaboration of Internal and Terminal Alkynes: Scope and Mechanistic Studies

B. Ansell, J. Spencer, O. Navarro, ACS Catal., 2016, 6, 2192−2196.   

Insights into the mechanism for gold catalysis: behaviour of gold(i) amide complexes in solution

Bobin, I. J. Day, S. M. Roe, E. M. E. Viseux, Dalton Trans, 2013, 42, 6592–11.










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