Heterocyclic compounds are cyclic molecular scaffolds composed of atoms of at least two different elements. Many important classes of molecules contain heterocycles, including nucleic acids, agrochemicals, organic conductors, many drugs used in the clinic and a number of natural and synthetic dyes and so the efficient synthesis of heterocyclic scaffolds is an important commercial and scientific activity.
The LabFact partners have developed approaches for the efficient preparation of diverse heterocycles using reagentless techniques.
Recent developments in chemical reactivity of N,N-dimethylenamino ketones as synthons for various heterocycles
Elaboration of Tetra-Orthogonally-Substituted Aromatic Scaffolds Towards Novel EGFR-Kinase Inhibitors
The Bohlmann-Rahtz pyridine synthesis: from discovery to applications